Whisk first three ingredients in a large mixing bowl.
Mix in meat and breadcrumbs. Season with salt and pepper, if desired.
Form into 4 patties, 1⁄2" thick.
Cook for 10–15 min on greased grill over medium-high heat or in a fry pan with lid closed, flipping once, or until cooked though and an instant read thermometer indicates a Food Safe internal temperature of 175° F.
Place burgers on buns and top with cheese and salsa.